Piracetam

Description

Piracetam Overview

Piracetam (chemical name: 2-oxo-1-pyrrolidinyl acetamide) is a synthetic compound in the racetam class. It was one of the first nootropic research chemicals developed and has been investigated extensively in laboratory and controlled experimental settings.

Chemical and Molecular Properties

PubChem CID	4843
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	2-Oxo-1-pyrrolidineacetamide 2-(2-Oxopyrrolidin-1-yl)acetamide 2-(2-Oxopyrrolidino)acetamide 1-Acetamido-2-pyrrolidinone
IUPAC	2-(2-oxopyrrolidin-1-yl)acetamide
CAS	7491-74-9
Labeling	Research Use Only (RUO), not for human or animal consumption
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO), not for human or animal consumption
Storage Temperature	Store in a controlled room temperature, typically between 15°C and 30°C (59°F to 86°F)

Mechanisms of Action

Piracetam's precise mechanism is not fully understood. Research suggests it acts via multiple pathways:

Membrane Fluidity Modulation

• Piracetam appears to increase the flexibility of neuronal and mitochondrial membranes.
• In laboratory models, this may help restore cellular function where membrane rigidity is pronounced.

Metabolic Enhancement

• Studies indicate potential enhancement of mitochondrial function, including improved membrane potential and ATP production.
• It may also reduce susceptibility to oxidative stress in experimental systems.

Neurotransmission Modulation

• Observed effects on cholinergic pathways (acetylcholine-associated) and glutamatergic systems (particularly AMPA receptors).
• These effects are investigated for their influence on synaptic signaling and cellular communication in research models.

Potential Research Applications

Piracetam is primarily used in in vitro and preclinical research to explore cellular, molecular, and physiological processes. Key research applications include:

Membrane and Cellular Studies

• Investigated for its effects on cellular membrane fluidity in neuronal and mitochondrial models.
• Used to examine how changes in membrane flexibility influence intracellular signaling and cellular responses under experimental conditions.

Mitochondrial and Metabolic Research

• Employed in studies assessing mitochondrial function, including membrane potential and ATP production in laboratory models.
• Used to investigate oxidative stress modulation and cellular resilience in controlled experiments.

Neurotransmission and Synaptic Signaling

• Studied for interactions with cholinergic pathways (acetylcholine-related) and glutamatergic systems (AMPA receptors) in research models.
• Useful for exploring synaptic signaling, plasticity, and neuronal communication in preclinical studies.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

 

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

References:

1. Muller, W., Eckert, G., & Eckert, A. (1999). Piracetam: novelty in a unique mode of action. Pharmacopsychiatry, 32(S 1), 2-9. https://doi.org/10.1055/s-2007-979230
2. Noorbala, A. A., Akhondzadeh, S., Davari-Ashtiani, R., & Amini-Nooshabadi, H. (1999). Piracetam in the treatment of schizophrenia: implications for the glutamate hypothesis of schizophrenia. Journal of Clinical Pharmacy and Therapeutics, 24(5), 369-374. https://doi.org/10.1046/j.1365-2710.1999.00238.x
3. Winblad, B. (2005). Piracetam: A review of pharmacological properties and clinical uses. CNS Drug Reviews, 11(2), 169–182. https://doi.org/10.1111/j.1527-3458.2005.tb00268.x