N-Acetyl Carnosine

Description

N-Acetyl Carnosine

Product Overview

N-Acetyl Carnosine is an acetylated derivative of the dipeptide L-carnosine. Structurally, it consists of β-alanine and L-histidine with an acetyl group attached to the nitrogen atom of the β-alanine residue. This modification alters the molecule’s stability and biochemical behavior compared with its parent compound.

The acetylation process produces a derivative that is more resistant to enzymatic degradation by carnosinase, an enzyme that rapidly breaks down L-carnosine in certain biological environments

Property	Data
Compound Name	N-Acetyl Carnosine
PubChem CID	439172
CAS Number	56353-15-2
Molecular Formula	C11H16N4O4
Molecular Weight	268.27 g/mol
Chemical Classification	Acetylated dipeptide
IUPAC Name	N-[(3-aminopropanoyl)-L-histidyl]acetamide
Synonyms	N-Acetyl-β-alanyl-L-histidine
Structure
Source Database	PubChem (NCBI)

Working Mechanism

In different research subjects, NAC has been shown to penetrate the cornea and reach the lens, where it helps neutralize reactive oxygen species (ROS). It may also reduce oxidative stress, which is a key factor in cataract formation and other age-related eye changes in experimental models.

Some preclinical models have indicated that NAC may help prevent the crosslinking and stiffening of lens proteins caused by glycation. Glycation appears to contribute to lens clouding.

Research Applications

N-acetyl carnosine has been used in experimental setups to study oxidative stress pathways and carbonyl chemistry. The researchers investigate how acetylated peptides affect metabolic events involving reactive aldehydes and oxidized lipids.

Protein glycation pathways are also being investigated. The chemical has been used in laboratory settings to assess how carbonyl-reactive peptides affect protein crosslinking and structural change.

Biochemical experiments also explore the compound's stability in environments where enzymatic degradation typically limits the persistence of small peptides. These models provide insight into how chemical modification of dipeptides alters their biochemical behavior.

Why Buy at PureRawz

When it comes to buying N-Acetyl Carnosine, Purerawz will never disappoint. We make sure that our customers have a smooth and hassle-free experience. Therefore, we provide them with third-party testing and standard quality N-Acetyl Carnosine.

Your satisfaction is our priority, thereby giving you a Certificate of Analysis with this product. Furthermore, we offer you safe payment options so that your transactions remain secure with us.

Note: N-Acetyl Carnosine distributed by PureRawz is provided exclusively as a research chemical. The compound has not received approval from the U.S. Food and Drug Administration (FDA) for therapeutic or veterinary use in this form.

Research Disclaimer

The information presented is intended for scientific reference purposes only.

By placing an order, you agree to the PureRawz Terms and Conditions. If you are not satisfied with your order, please contact support@staging.purerawz.co. 

ATTENTION: All products are FOR LABORATORY AND RESEARCH PURPOSES ONLY and NOT FOR HUMAN OR ANIMAL USE.

All experimental work should be conducted by qualified professionals and must comply with institutional regulatory oversight, such as IRB or IACUC guidelines when applicable.

References

Babizhayev, M. A. (2002). Biological activities of the natural imidazole-containing peptide carnosine in ophthalmic research. Drugs in R&D, 3(2), 87 103. https://pubmed.ncbi.nlm.nih.gov/12093303/

Hipkiss, A. R. (2009). Carnosine and its possible roles in nutrition and health. Advances in Food and Nutrition Research, 57, 87 154. https://pubmed.ncbi.nlm.nih.gov/19389612/

National Center for Biotechnology Information. (2024). N-Acetyl Carnosine compound summary. PubChem Database. https://pubchem.ncbi.nlm.nih.gov/compound/439172

ClinicalTrials.gov. (2024). Peptide antioxidant research database. https://clinicaltrials.govWelcome to GPTZero for Google Docs!