DMSO Dimethyl Sulfoxide – Solvent

Description

DMSO Dimethyl Sulfoxide (USP Grade) - Overview

Dimethyl sulfoxide (DMSO) is a natural, highly polar liquid derived from lignin in wood pulp. It has been used in the U.S. for over a century as a solvent and chemical vehicle due to its ability to penetrate biological membranes. It also has pharmacological effects, including analgesic and anti-inflammatory activity, which support certain topical applications.

Pharmaceutical-grade DMSO is FDA-approved for treating interstitial cystitis. It is also studied for protecting tissues during intravenous medication leakage and in research applications such as cryopreservation of cells and tissues.

DMSO has been explored as a dietary supplement and natural remedy. However, most claims outside approved medical uses lack strong scientific evidence. So, its non-approved applications are primarily limited to research studies.

Chemical Properties

Property	Information
CAS Number	67-68-5
Molecular Formula	C2H6OS
Molecular Mass	78.14 g/mol
Synonyms	dimethyl sulfoxide, DMSO, Methylsulfinylmethane, Dimethylsulfoxide
IUPAC Name	methylsulfinylmethane
Storage	25-30°C (59-86°F)

Mechanisms of Action

Dimethyl sulfoxide's exact mechanism of action is not fully understood, but it has several biological effects observed in laboratory research. It can act as an antioxidant, scavenging free radicals and reducing oxidative stress in some experimental models.

In addition, DMSO interacts with cell membranes. This makes them more fluid and permeable, which partly explains their role as a penetration enhancer and cryoprotectant in research settings. At different concentrations, it can influence membrane structure and support the transport of molecules across lipid layers. It can also modulate signaling pathways associated with inflammation and cellular responses.

Possible Applications of DMSO Dimethyl Sulfoxide

DMSO and Inflammation

In patients with arthritis and connective tissue injuries, dermal application of DMSO appears to provide rapid, temporary pain relief.

However, claims of anti-inflammatory effects or faster healing are currently unsubstantiated.

Dimethyl Sulfoxide and Arthritis

According to new double-blind research, after three weeks, a 25% dosage of DMSO in gel form reduced osteoarthritis pain much better than a placebo. DMSO appears to alleviate pain by suppressing the transmission of pain messages via nerves rather than mending injured joints.

Note: Dimethyl sulfoxide is FDA-approved for the treatment of interstitial cystitis. For all other uses, it is available only for research and experimental purposes.

Where to Buy DMSO (Dimethyl Sulfoxide)?

PureRawz supplies high-purity DMSO for laboratory and experimental research purposes. The compound is produced under controlled conditions to ensure consistency and reliability in research studies.

All products are tested through rigorous quality control. An independent third-party Certificate of Analysis (COA) verifies the compound’s identity, purity, and overall quality for research use.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY.

All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).

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Reference Links

PubChem. (2019). Dimethyl sulfoxide. @Pubchem; PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Dimethyl-sulfoxide

Swanson, B. N. (1985). Medical use of dimethyl sulfoxide (DMSO). Reviews in Clinical & Basic Pharmacology, 5(1-2), 1-33. https://pubmed.ncbi.nlm.nih.gov/3916302/