Description
CB-03-01 Powder Overview
CB-03-01 (commonly known as Clascoterone) is a synthetic steroidal compound. It is investigated in biochemical and pharmacological research. The compound is structurally related to corticosteroid derivatives. It is studied for its interaction with androgen receptor signaling pathways in experimental systems.
In laboratory environments, CB-03-01 is used as a reference compound. This is done to check androgen receptor–mediated cellular signaling and localized androgen-regulated biological processes. Researchers often examine this compound in controlled experimental models. They do it to analyze molecular mechanisms associated with receptor-ligand interactions and downstream signaling regulation.
In research models, CB-03-01 is commonly employed to explore:
- androgen receptor ligand-binding interactions
- regulation of lipid and sebaceous gland signaling pathways, and
- molecular mechanisms associated with localized androgen signaling (in in-vitro assays and preclinical models)
CB-03-01 powder formulations are supplied strictly as research materials intended for analytical and laboratory investigation.
CB-03-01 Powder
| Property | Description |
| Compound Name | CB-03-01 (Clascoterone) |
| Class | Androgen receptor antagonist |
| Molecular Formula | C24H34O5 |
| Molecular Weight | 402.5 g/mol |
| Research Category | Androgen receptor signaling research compound |
| Structural Class | Steroidal androgen receptor modulator |
| Formulation | Research-grade powder |
Mechanism of Action
Androgen Receptor Interaction
CB-03-01 is investigated in laboratory studies. This is done to see its interaction with androgen receptor proteins located in androgen-responsive tissues. These receptors function as ligand-activated transcription factors that regulate downstream gene expression following androgen binding.
Competitive Ligand Binding
In experimental systems, endogenous androgens, such as dihydrotestosterone (DHT), interact with androgen receptors to initiate signaling cascades that regulate lipid metabolism and cellular regulatory pathways. CB-03-01 is studied for its ability to compete with endogenous ligands for receptor binding sites in biochemical receptor-binding assays.
Modulation of Androgen-Related Signaling
In molecular research models, CB-03-01 is examined for its ability to influence androgen-dependent signaling processes by altering receptor activation and downstream transcriptional responses. These interactions are commonly investigated in studies focused on receptor pharmacology and intracellular signaling dynamics.
Research Applications
In controlled laboratory settings, CB-03-01 may be utilized for investigations involving:
- androgen receptor ligand-binding assays
- androgen-regulated gene expression pathway analysis
- sebaceous gland signaling pathway research models
- receptor pharmacology and steroidal ligand structure-activity studies
- cellular signaling investigations involving androgen-responsive pathways
All applications are strictly confined to experimental and analytical research environments.
Why Choose Purerawz?
Buy CB-03-01 powder for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each compound is supplied with an independent third-party Certificate of Analysis verifying identity, purity, and analytical specifications.
Note: CB-03-01 (C24H34O5) is an investigational compound currently undergoing scientific evaluation and has not been established as safe or effective for any therapeutic application.
Disclaimer
This information is for educational purposes only and does not constitute medical advice.
THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the Institutional Animal Care and Use Committee (IACUC) in accordance with the guidelines of the Animal Welfare Act (AWA).
Our content is intended to be used for informational purposes only. It is important to conduct independent analysis and review research from trusted sources before making any purchase decision.
By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our priority. If you are not fully satisfied with the product you received, please contact support@staging.purerawz.co/
ATTENTION: All products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.
References
Trifu V, Tiplica GS, Naumescu E, et al. Clascoterone topical cream for androgen-mediated dermatologic conditions - Journal of Drugs in Dermatology
https://pubmed.ncbi.nlm.nih.gov/30807938/
Hebert AA, Thiboutot DM, Stein Gold L, et al. Efficacy and safety of clascoterone cream in androgen-related skin conditions - Journal of the American Academy of Dermatology
https://pubmed.ncbi.nlm.nih.gov/33049370/
Dr. Helma Wennemers
Dr. Helma Wennemers is a globally recognized chemist shaping modern peptide science and molecular design through highly original research in applied biosciences.
Her work explores how precise molecular architecture can be engineered to create new functional systems in chemistry and life sciences. Her contributions continue to redefine contemporary chemical research through creativity, depth, and structural innovation.

