Cordyceps Sinensis

Description

Cordyceps sinensis Extract 

Product Information

Cordyceps are parasitic fungi from the Cordycipitaceae family. Because of their unique host-parasite lifecycle and the numerous secondary metabolites they produce, species in this genus have been studied in ecological and biochemical contexts. Cordyceps sinensis, a fungus that has traditionally been found in high-altitude regions of the Tibetan Plateau, is one of the better recognized species.

One of the most frequently studied molecules associated with Cordyceps species is cordycepin (3′-deoxyadenosine). Cordycepin has been examined in biochemical and pharmacological experiments because of its structural similarity to adenosine and its potential influence on cellular signaling pathways.

Property	Data
Compound Name	Cordycepin (3′-Deoxyadenosine)
PubChem CID	6303
CAS Number	73-03-0
Molecular Formula	C10H13N5O3
Molecular Weight	251.24 g/mol
Chemical Classification	Purine nucleoside analog
Source Database	PubChem (NCBI)

Working Mechanism

Cordycepin is known to participate in biochemical processes involving nucleic acid metabolism. Because the molecule resembles adenosine but lacks the 3′-hydroxyl group required for RNA chain elongation, it can interrupt RNA synthesis when incorporated into nucleic acid strands. This mechanism has made cordycepin useful in experimental work exploring transcription regulation and RNA stability.

Cordyceps extracts also contain additional compounds, including polysaccharides and sterols, which have been examined for their interactions with signaling proteins and inflammatory mediators. These investigations are typically performed using cell cultures or controlled experimental systems.

Research Applications

Laboratory work involving cordycepin has examined mitochondrial activity and cellular energy pathways, particularly those associated with ATP production. Because ATP functions as the primary energy carrier within cells, alterations in nucleotide metabolism are sometimes explored to understand broader metabolic responses.

Immunological signaling has also been studied in relation to Cordyceps metabolites. Some experiments have evaluated how cordycepin influences cytokine expression and immune cell activity in controlled models. These investigations aim to clarify how nucleoside analogs interact with transcription pathways and inflammatory mediators.

Other studies examine oxidative stress mechanisms. Fungal metabolites isolated from Cordyceps species have been analyzed for their interactions with reactive oxygen species and antioxidant defense systems in cultured cells. 

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Note: It is important to clarify that Cordyceps-derived extracts are not approved by the U.S. Food and Drug Administration (FDA) as medicinal treatments. Their study remains limited to experimental and analytical research settings. 

Research Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

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References

Cunningham, K. G., & Hutchinson, S. A. (1951). Cordycepin, a metabolic product from cultures of Cordyceps militaris. Nature, 166(4231), 949. https://pubmed.ncbi.nlm.nih.gov/14793310/

National Center for Biotechnology Information. (2024). Cordycepin compound summary. PubChem Database. https://pubchem.ncbi.nlm.nih.gov/compound/6303

Paterson, R. R. M. (2008). Cordyceps – A traditional Chinese medicine and another fungal therapeutic biofactory? Phytochemistry, 69(7), 1469-1495. https://pubmed.ncbi.nlm.nih.gov/18308564/

Zhou, X., Gong, Z., Su, Y., Lin, J., & Tang, K. (2009). Cordyceps fungi: Natural products and pharmacological functions. Journal of Pharmacy and Pharmacology, 61(3), 279-291. https://pubmed.ncbi.nlm.nih.gov/19298653/

ClinicalTrials.gov. (2024). Cordycepin related research database. https://clinicaltrials.gov