Cardarine (GW-501516)

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Description

 

Overview of Cardarine (GW-501516)

Cardarine (GW-501516) is a  a metabolic modulator, it helps researchers understand energy production and fat oxidation in muscle tissue.

Cardarine is a Peroxisome Proliferator-Activated Receptor delta (PPARδ) agonist and is distinct from SARMs (selective androgen receptor modulators). 

Chemical and Molecular Properties

Cardarine
PubChem CID 9803963
Molecular Formula C21H18F3NO3S2
Molecular Weight 435.5 g/mol
Synonyms GW501516, GW 501516, Endurobol
IUPAC 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid
CAS 317318-70-0
Labeling Research Use Only (RUO), not for human or animal consumption.
Chemical Structure Depiction

 

Purity ≥98%
Classification PPARδ (Peroxisome proliferator-activated receptor delta) agonist; research chemical
Storage Temperature  Lyophilized: −20 °C or colder
Solubility  Soluble in DMSO; low solubility in water
Safety Handle with gloves, a lab coat, eye protection; use a fume hood if dust/aerosol is possible

Cardarine Mechanism of Action

Cardarine interacts with the peroxisome proliferator-activated receptor delta (PPARδ), a nuclear receptor involved in regulating metabolic gene expression. After binding to this receptor, the receptor–ligand complex influences transcription pathways associated with cellular energy management.

Activation of PPARδ has been observed to alter the expression of genes involved in fatty acid transport, mitochondrial activity, and lipid processing. Through this receptor-mediated signaling pathway, Cardarine is commonly examined in experimental models that investigate metabolic regulation at the cellular level.

Cardarine Research Application

Studies have explored the effects of Cardarine in lab settings and animal models, looking at its role in:

  • Fatty acid burning.
  • Glucose metabolism regulation.
  • Energy use at the molecular level.

These effects were observed in experiments and may not apply to broader use.

Why Choose PureRawz for Cardarine (GW-501516)?

Buy Cardarine for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each research compound comes with a Certificate of Analysis for verification of purity and concentration.

Note:

Cardarine is an investigational compound currently undergoing clinical evaluation and has not been established as safe or effective for any therapeutic use.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.

Reference Links

Bioscience, E. (2020c, December 14). What is Cardarine? A Comprehensive GW-501516 Review. ELV BIOSCIENCE

https://elvbio.com/what-is-cardarine-a-comprehensive-gw501516-review/

PubChem. (n.d.-c). GW 501516. PubChem.  https://pubchem.ncbi.nlm.nih.gov/compound/9803963

Kadayat, T. M., Shrestha, A., Jeon, Y. H., An, H., Kim, J., Cho, S. J., & Chin, J. (2020c).  Targeting Peroxisome Proliferator-Activated Receptor Delta (PPARΔ): A Medicinal  Chemistry perspective. Journal of Medicinal Chemistry, 63(18), 10109‑10134.  https://doi.org/10.1021/acs.jmedchem.9b01882

Dr. Helma Wennemers

Dr. Helma Wennemers is a globally recognized chemist shaping modern peptide science and molecular design through highly original research in applied biosciences.

Her work explores how precise molecular architecture can be engineered to create new functional systems in chemistry and life sciences. Her contributions continue to redefine contemporary chemical research through creativity, depth, and structural innovation.

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