Alpha GPC

Description

Overview of Alpha GPC

Alpha GPC is a cholinergic compound involved in cellular and biochemical pathways. It functions as a precursor in the synthesis of acetylcholine, a key neurotransmitter. Pure Rawz provides Alpha GPC strictly for laboratory and research applications.

Chemical and Molecular Activities

Alpha GPC (L-Alpha glycerylphosphorylcholine) is a choline-containing compound. It participates in cellular signaling and membrane phospholipid pathways. Alpha GPC is studied for its effects on acetylcholine synthesis and related molecular mechanisms in experimental systems.

The complete chemical profile is provided in the table below for reference.

Alpha GPC
PubChem CID	11234
Molecular Formula	C8H20NO6P
Molecular Weight	257.22 g/mol
Synonyms	Alpha-GPC, L-alpha-Glycerylphosphorylcholine, Glycerophosphocholine, Choline alfoscerate, L-alpha-Lecithin, Sn-3-GPC
IUPAC	[(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
CAS	28319-77-9
Labeling	Research Use Only (RUO), not for human or animal consumption.
Chemical Structure Depiction
Purity	≥98%
Classification	Cholinergic compound; phospholipid derivative; research chemical
Storage Temperature	Lyophilized: –20 °C or colder
Solubility	Water, DMSO (research-grade solvents)
Safety	Handle with gloves, a lab coat, eye protection; use a fume hood if dust/aerosol is possible

Mechanism of Action

Alpha GPC functions by supporting acetylcholine synthesis. In biochemical pathways, it can be metabolized to phosphatidylcholine, which interacts with cholinergic synaptic sites. Research in cell cultures and animal models indicates that Alpha GPC may modulate neurotransmitter systems, including:

• Acetylcholine: Acts as a precursor, supporting synthesis and release at cholinergic synapses.
• GABA (Gamma-aminobutyric acid): May influence inhibitory neurotransmission and receptor signaling pathways.
• Dopamine: Experimental models suggest modulation of dopaminergic signaling pathways in specific neural regions.
• Serotonin: Laboratory studies indicate possible effects on serotonergic signaling.
• Growth Hormone (GH) pathways: Observed in experimental settings to interact with biochemical pathways influencing GH secretion.

Research Application 

Studies involving Alpha GPC have explored its molecular interactions, receptor activity, and cellular signaling pathways. Research has included:

• Neuronal signaling: Modulation of acetylcholine synthesis and synaptic release.
• Neurotransmitter interactions: Observed effects on GABAergic, dopaminergic, and serotonergic systems in controlled laboratory models.
• Biochemical metabolism: Conversion to phosphatidylcholine and subsequent participation in choline-related metabolic pathways.

Pure Rawz emphasizes that Alpha GPC is intended for in vitro and laboratory research only. No claims are made regarding physiological or therapeutic effects in humans or animals.

Why Choose PureRawz for Alpha GPC?

Buy Alpha GPC for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each research compound comes with a Certificate of Analysis for verification of purity and concentration.

Note:

Alpha GPC is an investigational compound currently undergoing clinical evaluation and has not been established as safe or effective for any therapeutic use

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Reference Links

PubChem. (n.d.-b). Glycerophosphocholine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/11234

Li, J., Zhang, J., Wang, Y., Yang, Y., Su, Y., Gu, L., & Chang, C. (2025).L–Alpha–Glycerylphosphorylcholine (L–Α–GPC): A comprehensive review of its preparation techniques and versatile biological effects. Journal of Food Science, 90(6), e70338. https://doi.org/10.1111/1750-3841.70338

Tardner, P. (2024, June 17). Alpha-GPC: King Of The Cholinergics?.IJEST.https://www.ijest.org/nootropics/alpha-gpc/