4F-Phenibut HCI

Description

4F-Phenibut-HCl Overview

4-Fluorophenibut HCl is a synthetic research compound and a fluorinated derivative of phenibut. The addition of a fluorine atom differentiates it from phenibut and may influence receptor interactions and metabolic stability, although further studies are required to fully understand its properties.

Chemical and Molecular Properties

PubChem CID	121237598
Molecular Formula	C10H12FNO2 HCl
Molecular Weight	233.7 g.mol
Synonyms	F-Phenibut, 4-Fluorophenibut, Fluorobut
IUPAC	4-amino-3-(4-fluorophenyl)butanoic acid;hydrochloride
CAS	1858241-03-8
Labeling	Research Use Only (RUO), not for human or animal consumption
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO)
Storage Temperature	Store at temperature -20°C (-4°F)

Mechanisms of Action

Structurally similar to phenibut, 4-Fluorophenibut HCl is believed to function as a GABA receptor agonist. Preclinical studies suggest that its fluorinated structure could affect:

• Receptor binding affinity
• Metabolic stability
• GABAergic signaling pathways

Current research focuses on its potential influence on:

• CNS neurotransmitter regulation
• Anxiolytic-like responses in preclinical models
• Modulation of GABAergic signaling

Potential Research Applications

4-Fluorophenibut HCl is primarily utilized in preclinical and laboratory research to investigate its pharmacological properties and effects on GABAergic systems. Potential research applications include:

• GABA Receptor Signaling Studies

Exploration of its activity as a GABA receptor agonist, including receptor binding affinity, downstream signaling, and interaction with GABAergic pathways.

• Neurotransmitter Regulation Research

Investigation into potential modulation of central nervous system neurotransmitters and related cellular responses in controlled preclinical models.

• Behavioral Model Studies

Examination of its effects on anxiety-like or stress-related behaviors in research models, under strictly regulated laboratory conditions.

• Comparative Pharmacology

Comparison with phenibut and other structurally related compounds to assess the impact of fluorination on receptor activity, metabolic stability, and pharmacodynamics in vitro and in vivo preclinical studies.

• Neurochemical and Mechanistic Studies

Characterization of downstream intracellular signaling pathways and molecular mechanisms associated with GABA receptor activation.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

References:

1. Irie, T., Yamazaki, D., & Kikura-Hanajiri, R. (2020). F-phenibut (β-(4-Fluorophenyl)-GABA), a potent GABAB receptor agonist, activates an outward-rectifying K+ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells. European Journal of Pharmacology, 884, 173437. https://doi.org/10.1016/j.ejphar.2020.173437
2. Lapin, I. (2001). Phenibut (β-Phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Reviews, 7(4), 471-481. https://doi.org/10.1111/j.1527-3458.2001.tb00211.x