Phenibut HCL

Description

Overview of Phenibut HCl

Phenibut HCl (B-Phenyl-Y-aminobutyric acid hydrochloride) is a synthetic GABA analog. It has the addition of a phenyl ring to the Y-aminobutyric acid structure. The hydrochloride salt form improves stability and handling in laboratory environments.

This compound has been described in scientific literature for its interaction with inhibitory neurotransmission pathways. This is both true in experimental and preclinical models. Current understanding is derived primarily from in vitro studies, analytical investigations, and controlled laboratory research settings.

Phenibut HCl is supplied as a high-purity crystalline powder intended strictly for laboratory and research applications.

Chemical and Molecular Properties

Property	Description
Chemical Name	B-Phenyl-Y-aminobutyric acid hydrochloride
Molecular Formula	C10H13NO2.HCl
Molecular Weight	215.68 g/mol
CAS Number	1078-21-3
Structure	GABA backbone with phenyl substitution at the β-position
Appearance	White crystalline powder
Solubility	Soluble in water (hydrochloride salt form)
Classification	GABA analog (research compound)

Working Mechanism of Phenibut HCl

Structural Modification and Receptor Interaction

Phenibut HCl is structurally derived from Y-aminobutyric acid (GABA) through B-phenyl substitution. This modification alters its physicochemical properties. This influences its interaction profile in experimental systems.

Preclinical receptor binding studies indicate affinity primarily toward GABA(B) receptor subtypes. Interaction with these metabotropic receptors has been observed in controlled laboratory models.

Modulation of Inhibitory Signaling

In vitro and experimental research models suggest that Phenibut HCl may modulate inhibitory neurotransmission pathways through GABAergic signaling mechanisms. Activation of GABA(B) receptors is associated with downstream intracellular signaling cascades involving G-protein-coupled pathways.

These mechanistic observations are based on experimental data and are not indicative of clinical outcomes.

Analytical and Pharmacokinetic Investigations

Phenibut HCl has also been evaluated in laboratory research for analytical quantification in biological matrices. Studies have focused on chromatographic identification and detection methods to understand its chemical stability and distribution characteristics in experimental systems.

Phenibut HCl Research Applications (Laboratory Use Only)

Phenibut HCl is utilized in laboratory environments for:

• Investigational studies involving GABA(B) receptor activity
• In vitro receptor binding assays
• Experimental models exploring inhibitory neurotransmission pathways
• Analytical chemistry research involving compound detection and validation
• Preclinical pharmacodynamic and mechanistic studies

All applications are limited strictly to controlled laboratory research settings. No information presented here should be interpreted as supporting therapeutic, veterinary, or human use.

Why Choose Purerawz for Phenibut HCl?

Buy Phenibut HCl for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each research compound comes with a Certificate of Analysis for verification of purity and concentration.

Note:
Phenibut HCl (B-Phenyl-Y-aminobutyric acid hydrochloride) is an investigational compound currently undergoing clinical evaluation and has not been established as safe or effective for any therapeutic use.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Reference Links

Lapin, I. (2001). Phenibut (B-phenyl-GABA): A tranquilizer and nootropic drug. CNS Drug Reviews, 7(4), 471-481. https://doi.org/10.1111/j.1527-3458.2001.tb00211.x/

Shulgina, G. I. (1986). Pharmacological properties of phenibut. Bulletin of Experimental Biology and Medicine, 102(5), 1381-1383. https://doi.org/10.1007/BF00841264/