TUDCA

Description

TUDCA (Tauroursodeoxycholic Acid) 

Product Overview

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated bile acid derivative that has been widely investigated in biochemical and cellular research. It is formed by the conjugation of ursodeoxycholic acid (UDCA) with the amino acid taurine and is naturally present in small amounts in bile acid pools in certain mammals.

TUDCA has drawn interest in experimental research looking at cell survival pathways, mitochondrial function, and bile acid signaling systems since bile acids are crucial regulators of lipid metabolism, cellular stress signaling, and digestive functions.

PureRawz supplies TUDCA strictly for laboratory and scientific research purposes. This is not FDA-approved and should not be used as a dietary supplement.

Property	Description
Compound Name	Tauroursodeoxycholic Acid (TUDCA)
Chemical Class	Taurine-conjugated bile acid
Molecular Formula	C26H45NO6S
Molecular Weight	499.7 g/mol
CAS Number	14605-22-2
Appearance	White to off-white powder
Solubility	Soluble in water and polar solvents
IUPAC	2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid

Mechanism of Action

Research suggests that TUDCA may interact with several cellular pathways involved in stress regulation and metabolic homeostasis.

In experimental systems, investigators have examined how TUDCA may influence endoplasmic reticulum (ER) stress responses, a cellular process associated with protein folding and quality control. Disruptions in ER function can lead to activation of apoptosis signaling pathways.

Additionally, because TUDCA is a bile acid derivative, researchers study its role in bile acid metabolism and transport systems, which are important for lipid digestion and hepatic physiology.

Research Applications

TUDCA has been studied by researchers in many clinical settings, such as:

• Research on the signaling mechanisms involved in endoplasmic reticulum stress
• Studies on oxidative stress reactions and mitochondrial stability
• Experimental models assessing cellular survival and apoptotic regulation
• Studies of liver physiology and bile acid metabolism
• Laboratory studies looking at models of neurodegenerative diseases
• Research on cellular adaptability and metabolic signaling pathways

Why Buy TUDCA from PureRawz?

PureRawz provides research-grade compounds tested for identity and purity. Each batch of TUDCA is accompanied by a Certificate of Analysis (COA) for verification. Orders of $100 or more qualify for free shipping, and PureRawz periodically offers promotional discounts for research supply purchases.

Research Disclaimer

The information presented here is intended for educational and research reference purposes only.

All products sold by PureRawz are supplied strictly for laboratory and scientific research use and are not intended for human or veterinary consumption.

Research involving this compound should be conducted only by qualified professionals and must comply with applicable regulatory guidelines, including Institutional Review Board (IRB) or Institutional Animal Care and Use Committee (IACUC) oversight where appropriate.

For product information, support, or order inquiries: support@staging.purerawz.co. 

References

Amaral, J. D., Viana, R. J., Ramalho, R. M., Steer, C. J., & Rodrigues, C. M. P. (2009). Bile acids: Regulation of apoptosis by ursodeoxycholic acid. Journal of Lipid Research, 50(9), 1721 1734. https://doi.org/10.1194/jlr.R900011-JLR200

Keene, C. D., Rodrigues, C. M., Eich, T., et al. (2002). Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic mouse model of Huntington’s disease. Proceedings of the National Academy of Sciences, 99(16), 10671 10676.

Vang, S., Longley, K., Steer, C. J., & Low, W. C. (2014). The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine, 3(3), 58 69.