Phenibut FAA

Description

Phenibut FAA Overview

Phenibut FAA (Free Amino Acid form) is a synthetic compound derived from beta-phenyl-gamma-aminobutyric acid (β-phenyl-GABA). It was originally synthesized in Eastern Europe for scientific investigation into central nervous system (CNS) receptor activity and neurochemical signaling.

Phenibut FAA differs structurally from its hydrochloride counterpart (Phenibut HCl) in that it exists in its free amino acid form. This distinction alters certain physicochemical characteristics, including acidity and solubility parameters, which may influence how it is utilized in controlled laboratory environments.

Chemical and Molecular Properties

PubChem CID	14113
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	Phenibut 1078-21-3 Fenibut 4-Amino-3-phenylbutyric acid PhGaba
IUPAC	4-amino-3-phenylbutanoic acid
CAS	1078-21-3
Labeling	Research Use Only (RUO), not for human or animal consumption.
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO)
Storage Temperature	~Room Temperature: 68°F and 77°F (20°C to 25°C) ~Refrigerated: 36°F and 46°F (2°C to 8°C)

Mechanisms of Action

In experimental models, Phenibut FAA has been evaluated for its interaction with gamma-aminobutyric acid type B (GABA-B) receptors, which are involved in inhibitory neurotransmission within the central nervous system.

Preclinical investigations suggest that:

• Phenibut FAA may bind to GABA-B receptor sites in controlled laboratory assays.
• It has been examined for its influence on inhibitory signaling pathways.
• Some neurochemical studies explore its potential modulation of dopamine-related pathways.

The combined investigation of GABA-B receptor interaction and dopaminergic signaling has made Phenibut FAA a compound of interest in neuropharmacology research settings. Ongoing studies continue to evaluate receptor affinity, downstream signaling cascades, and broader neurochemical activity.

Potential Research Applications

Phenibut FAA has been studied in laboratory and preclinical environments for its potential involvement in:

• GABA-B receptor signaling mechanisms
• Neurotransmitter modulation models
• Experimental stress-response paradigms
• Behavioral research frameworks involving inhibitory neurotransmission
• Neurochemical pathway mapping in controlled in vitro and animal models

Researchers also explore its structural and receptor-binding properties when comparing free amino acid forms to salt-based analogs in analytical assays.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@staging.purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

References:

1. Lapin, I. (2001). Phenibut (β-Phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Reviews,7(4),471-481. https://doi.org/10.1111/j.1527-3458.2001.tb00211.x
2. Irie, T., Yamazaki, D., & Kikura-Hanajiri, R. (2020). F-phenibut (β-(4-Fluorophenyl)-GABA), a potent GABAB receptor agonist, activates an outward-rectifying K+ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells. European Journal of Pharmacology, 884, 173437. https://doi.org/10.1016/j.ejphar.2020.173437